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Seth Shipman

My graduate work in the Nicoll lab has given me a deep respect for the synapse and for the craft of electrophysiology. My research has been divided into two distinct directions: one that focuses on the role of the postsynaptic adhesion molecule neuroligin in the formation, maintenance, and plasticity of synapses; and another that is aimed at understanding the mechanism by which individual pyramidal neurons control the relative strength of synapses distributed across their dendritic arbors. My plan is to continue to study neurons using elec tro physiology with the goal of understanding the cellular basis of neuropsychiatric disease.

Before coming to UCSF, I studied neuroscience at Wesleyan University, where I worked with Harry Sinnamon, recording local field potentials and single units using extracellular electrodes implanted in the hippocampi of rats trained to perform complex appetitive behaviors. Next, I worked at the Olin Neuropsychiatry Research Center with Robert Astur, conducting behavioral and functional magnetic resonance imaging studies on healthy and psychiatric human populations.

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